Settings and Calibrating Joysticks and ESC´s

Hello everybody,
I have a Herelink and a Cube Orange configured as Arducopter v 4.03
When calibrating, I have to switch the channels for gas and pitch to reverse in Herelink so that they are displayed correctly in Mission Planner.
In the Herelink app, the ad is still going upside down, although they are now displayed correctly in Mission Planner.
In addition, I wanted to ask if you have to set the hook in the app on the parameter “Throttle Center to zero”?

How can I calibrate the ESCs now? With Mission Planner on the PC? With the Herelink Apps Solex or QGroundControl?
Why is it please?
Thank you for your help!