The Orange+ has JST-GH as the I2C2 connector which is not compatible with the DS13 connectors for the I2C on Pixhawk 4 models. This poses a problem adapting older 4525D air speed sensors for use on the Orange+. Tried to patch a JST-GH on a 4525D but so far I get nothing but failure from the sensor input in QGround control.
Works fine, make sure the connections are correct.