Orange CUBE starts only one motor

Electronic Speed Controller (ESC) Calibration — Copter documentation.

  • Some ESCs like the DJI Opto ESCs do not require and do not support calibration, so skip this page completely.

I guess you are not suppose to calibrate DJI Opto ESCs as normal Ardupilot ESC calibration? Maybe you can try to reset them to factory default then try again.